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Female fertility and the genital microbiota (the microbiome)

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Key Points		see Q&A
200	Female samples were predominantly colonised by Lactobacillus species, particularly in the lower genital tract,
201	Male samples exhibited greater microbial diversity (including bacteria linked to bacterial vaginosis), with only limited evidence of inter-partner microbiota transmission

	TextBook
	The complementary seminovaginal microbiome in health and disease
	DOI:10.1016/j.rbmo.2024.104707 by Reproductive BioMedicine Online in 2024			[1351]
	The evidence for placental microbiome and its composition in healthy pregnancies: A systematic review
	DOI:10.1016/j.jri.2021.103455 by Journal of Reproductive Immunology in 2022			[550]
	The Impact of the Female Genital Microbiota on the Outcome of Assisted Reproduction Treatments (2023)
	DOI:10.3390/microorganisms11061443 by Microorganisms in 2023			[175]
	Vaginal microbiome in obesity and its impact on reproduction (2023)
	DOI:10.1016/j.bpobgyn.2023.102365 by Best Practice & Research Clinical Endocrinology & Metabolism in 202			[174]

	Recent Publications
	Genital microbiota in infertile couples
	DOI:10.1016/j.rbmo.2025.105056 by Reproductive BioMedicine Online in 2025			[2735]
	Human Cervix Chip: A Preclinical Model for Studying the Role of the Cervical Mucosa and Microbiome in Female Reproductive Health
	DOI:10.1002/bies.70014 by BioEssays in 2025			[2731]
	Human embryo implantation: The complex interplay between endometrial receptivity and the microbiome
	DOI:10.1016/j.jri.2025.104440 by Journal of Reproductive Immunology in 2025			[2532]
	Differential characteristics of vaginal versus endometrial microbiota in IVF patients
	DOI:10.1038/s41598-024-82466-9 by Scientific Reports in 2024			[2444]
	The complementary seminovaginal microbiome in health and disease
	DOI:10.1016/j.rbmo.2024.104707 by Reproductive BioMedicine Online in 2024			[2348]
	Methodological approaches in 16S sequencing of female reproductive tract in fertility patients: a review
	DOI:10.1007/s10815-024-03292-6 by Journal of Assisted Reproduction and Genetics in 2024			[2179]
	Clinical Applicability of Microbiota Sampling in a Subfertile Population: Urine versus Vagina
	DOI:10.3390/microorganisms12091789 by Microorganisms in 2024			[2053]

	Webinars
	The Microbiome in Infertility [ASPIRE#13]
	ASPIRE

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